AVPR2 antibody (C-Term)

Catalog No. ABIN929264

The Rabbit Polyclonal anti-AVPR2 antibody has been validated for WB. It is suitable to detect AVPR2 in samples from Human. There is 1 publication available.

Quick Overview for AVPR2 antibody (C-Term) (ABIN929264)

Target: AVPR2 (Arginine Vasopressin Receptor 2 (AVPR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AVPR2 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: AVPR2 antibody was raised in rabbit using the C terminal of AVPR2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

References for anti-AVPR2 antibody (ABIN929264)

Canal, Wilkinson, Cooper, Wraith, Wynn, Bigger: "Circadian rhythm and suprachiasmatic nucleus alterations in the mouse model of mucopolysaccharidosis IIIB." in: Behavioural brain research, Vol. 209, Issue 2, pp. 212-20, (2010) (PubMed).

Target Details for AVPR2

Target: AVPR2 (Arginine Vasopressin Receptor 2 (AVPR2))

Alternative Name: AVPR2

Background: This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. Synonyms: Polyclonal AVPR2 antibody, Anti-AVPR2 antibody, arginine vasopressin receptor 2 antibody, ADHR antibody, DI1 antibody, DIR antibody, DIR3 antibody, MGC126533 antibody, MGC138386 antibody, NDI antibody, V2R antibody.

Pathways: cAMP Metabolic Process